Flexible Proteins at the Origin of Life

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Flexible Proteins at the Origin of Life

Almost all modern proteins possess well-defined, relatively rigid scaffolds that provide structural preorganization for desired functions. Such scaffolds require the sufficient length of a polypeptide chain and extensive evolutionary optimization. How ancestral proteins attained functionality, even though they were most likely markedly smaller than their contemporary descendants, remains a majo...

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ژورنال

عنوان ژورنال: Life

سال: 2017

ISSN: 2075-1729

DOI: 10.3390/life7020023